Trial · Schoemaker et al., Nutrients (2022)
Prebiotic Galacto-Oligosaccharides Impact Stool Frequency and Fecal Microbiota in Self-Reported Constipated Adults(opens in a new tab)
- Findings and study population
- 132 self-reported constipated adults, 94% women, received labeled 11 or 5.5 g/day GOS or control for three weeks. Overall primary stool-frequency differences were not significant (p=.095; per-protocol p=.184); stool consistency, constipation scores and PAC-SYM also showed no group differences.
- Limitations and differences from this claim
- The ≤3/week subgroup result (98 participants, p=.027) was post hoc. Microbiota changes do not prove improved health. The lactose-containing preparation excluded lactose intolerance/milk allergy. FrieslandCampina funded the study; five authors were employees.
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